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Open access Aug 2026

Plasma mitochondrial-associated proteins scale with illness severity and predict outcome in suspected sepsis

Mitochondrial dysfunction has been implicated in sepsis-related organ failure. We investigated whether plasma profiles of mitochondrial-associated proteins are associated with illness severity and short-term outcomes and explored whether they reveal distinct mitochondrial subphenotypes. In this post hoc analysis of the...

Cristian J. Meems, F. V. van Beuningen, Britt A. Coenen et al. · 0 citations
Open access Sep 2026

Implications of different SOFA score variants for outcome prediction in emergency department patients with an infection: a multicenter cohort study.

BACKGROUND The Sequential Organ Failure Assessment (SOFA) score estimates mortality risk and ICU admission in Emergency Department (ED) patients with infection, but not all parameters are routinely available outside the ICU. Several adaptations have been proposed, yet their impact on prognostic performance remains uncl...

T. J. van der Aart, Carolina Hincapié-Osorno, Isaac Santiago Arango-Gil et al. · 0 citations
#machine learning Preprint Sep 2026

When Does Synergy Help Active Feature Acquisition? A PID-Based Study

SynAFA, a state-dependent AFA policy that combines pairwise joint information and conditional information, with Partial Information Decomposition (PID) characterizing its information structure is introduced, with performance is heterogeneous.

Jie Li, M. Dhali, H. Bouma · 0 citations

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