Enlarged perivascular spaces (ePVS) are small, sparse MRI-visible markers of cerebral small vessel disease and brain ageing. Their size, low contrast, and severe foreground-background imbalance make automated segmentation challenging. Existing methods are mainly cross-sectional and do not model temporal consistency, li...
S. Hayashi, Lei Fan, Jiyang Jiang et al.· Journal of imaging informati...· 0 citations
BACKGROUND
Late-life depression (LLD) is associated with increased risk of cognitive decline and dementia, yet clinically relevant neuroimaging markers of short-term cognitive decline remain uncertain.
METHODS
We conducted a two-stage study. In the Shanghai Action to Prevent the Elderly from Dementia (SHAPE) cohort,...
Chaoyue Guo, Yuan Fang, Qi Qiu et al.· International Psychogeriatri...· 0 citations
BACKGROUND
Neighbourhood environmental features, including green and blue spaces, access to amenities, traffic, and ambient air pollution, may influence mental health in later life. Depression in older adults is associated with morbidity, cognitive decline, and reduced quality of life. While cross-sectional studies hav...
S. Reppermund, A. Matison, S. Röhr et al.· Journal of Affective Disorde...· 0 citations
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