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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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H. Burridge

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Open access Aug 2026

Age and CMV are not associated with clinical or immunological response to immune checkpoint blockade

Ageing and cytomegalovirus (CMV) infection drive major alterations to T-cell immunity. Age is also associated with an increased risk of cancers including melanoma, which is treated with T-cell modifying immune checkpoint blockade (ICB). However, the extent to which age, CMV, and treatment-induced immune changes interac...

J. M. Edwards, S. Senthi, R. Smith et al. · 0 citations

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