Author

H. Chen

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Open access Sep 2026

Valproate-induced hyperammonemic encephalopathy versus asymptomatic hyperammonemia in adults with epilepsy: a cross-sectional study

Background and Objective: To compare clinical features of valproate (VPA)-induced hyperammonemic encephalopathy and asymptomatic hyperammonemia to inform monitoring strategies. Methods: This cross-sectional study at Affiliated Hospital of Jiangsu University included 25 adults with epilepsy hospitalized between January...

H. Chen, X. Wang · medRxiv · 0 citations

Review Open access Sep 2026

Thermal variability and the geography of optimal temperature for child survival: childhood respiratory-infection mortality in 171 countries: a systematic analysis of the Global Burden of Disease Study 2023 and the C-LSAT high-resolution climate dataset

Background In adults, cold-attributable mortality exceeds heat-attributable mortality roughly 17-fold. Child-specific evidence has begun to emerge only recently - a nationwide Brazilian case-crossover study located the minimum mortality temperature (MMT) for under-five deaths, and a 56-country survey-based analysis lin...

D. Li, J. Liu, S. Sun et al. · medRxiv · 0 citations

Open access Sep 2026

Diversifying deaths: the shifting spectrum of childhood respiratory infectious mortality, 1990-2023: a systematic analysis of the Global Burden of Disease Study 2023

Background Childhood respiratory infectious deaths are partitioned across four Global Burden of Disease cause modules-26 etiological attributions within lower respiratory infections, tuberculosis, COVID-19, and whooping cough-never jointly reported. Whether the structure of this combined mortality spectrum has changed...

D. Li, H. Chen, Y. Miao et al. · medRxiv · 0 citations