APOE4 moderates the association of sleep disturbance with cerebral amyloid burden but not with clinical conversion in cognitively normal older adults.
BackgroundSleep disturbance has been linked to Alzheimer's disease (AD), but whether its relationships with cerebral amyloid-β (Aβ) pathology and clinical progression are modified by APOE ε4 (APOE4) carrier status in cognitively normal elderly remains unclear.ObjectiveTo examine APOE4 moderation of the associations of...