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H. Endo

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Open access Sep 2026

MA-5 attenuates disease-associated transcriptomic aging and pathological microglial states in Gaucher disease

Overall, MA-5 suppresses neuroinflammation and reverses accelerated transcriptomic aging, supporting its potential as a therapeutic strategy for GD and other lysosomal storage disorders, as well as for diseases characterized by mitochondrial dysfunction, chronic inflammation, and pathological accumulation.

Y. Tongu, Tomoko Kasahara, Kohta Nakamura et al. · 0 citations
Open access Jul 2026

Postoperative reduction of anti-seizure medication is associated with cognitive improvement in seizure-free patients after anterior temporal lobectomy.

Postoperative ASM reduction was associated with domain-specific cognitive improvement following ATL, particularly in WM, which support ASM tapering as a potentially modifiable factor influencing postoperative cognitive outcomes.

Kazushi Ukishiro, S. Osawa, M. Ogawa et al. · 0 citations

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