Author

H. F. Hetta

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Sep 2026

Nanovesicular Spanlastics Thermosensitive Gel for the Ocular Delivery of Voriconazole: Development, Ex Vivo Transcorneal Permeability, and In Vivo Evaluation in a Rabbit Model of Fungal Keratitis

Fungal keratitis remains a leading cause of corneal blindness and eye loss worldwide. Conventional antifungal preparations such as those of voriconazole (VCZ) are often limited by rapid precorneal drug loss and poor corneal penetration, leading to suboptimal therapeutic outcomes. This study aimed to address these limit...

G. Soliman, Ayman Salama, Mona Qushawy et al. · AAPS PharmSciTech · 0 citations

Review Sep 2026

Pharmaceutical innovation in advanced nanomedicine for the treatment of hypervirulent and multidrug-resistant Klebsiella pneumoniae infections

H. F. Hetta, Fawaz E. Alanazi, Hanan M. Alshareef et al. · Archives of Microbiology · 0 citations

Open access Aug 2026

Antimicrobial and Anti-inflammatory Potential of Thermoresponsive In situ Gel Loaded with Metronidazole Microsponges for Localized Treatment of Periodontitis

MSPs-loaded in situ gel represents a promising vehicle for MTZ to treat periodontitis and in vivo studies on rats revealed that this gel is an effective and innovative approach to treating periodontitis.

Eman S. Abd El-Reheim, Khaled M. A. Hassanein, H. F. Hetta et al. · Journal of Pharmaceutical In... · 0 citations