Author

H. Fujigaki

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Open access Sep 2026

425. Maternal immune activation induces neurodevelopmental impairments of adult offspring through alterations in tryptophane-kynurenine pathway in the placenta

Abstract Background Maternal immune activation (MIA) is recognized as one of the significant environmental risk factors for neuropsychiatric disorders such as schizophrenia in adult offspring. However, the pathophysiological mechanisms remain unknown. Aims & Objectives The tryptophan (TRP)-kynurenine (KYN) pathway, inf...

A. Mouri, M. Hasegawa, M. Niijima et al. · International Journal of Neu... · 0 citations

Open access Aug 2026

Monoclonal Antibody-Based ELISA Quantification of Serum Methylglyoxal-Derived Hydroimidazolone-1

Background/Objectives: Methylglyoxal-derived hydroimidazolone-1 (MG-H1), an advanced glycation end product, has implications in the pathogenesis of diabetic kidney disease (DKD). Although liquid chromatography–mass spectrometry is the current gold standard for quantifying MG-H1, its overall complexity limits its utilit...

Jun Nojima, Masatsuna Tasaka, H. Fujigaki et al. · Diagnostics · 0 citations