Icariin-Strontium nanoparticles induce apoptosis accompanied by autophagy in gastric cancer through PI3K/Akt/NF-kB suppression and mitochondrial dysfunction.
The combined data indicate that IR-SrNPs are a highly promising and efficacious nanotherapeutic treatment for gastric cancer, employing a dual-targeting approach to attenuate the PI3K/Akt pathway.