Engineering a multifunctional LL37-TP5 hybrid peptide with potent antimicrobial endotoxin-neutralizing and anti-inflammatory properties
The increasing prevalence of antimicrobial resistance and endotoxin-mediated inflammation highlights the need for alternative therapeutic strategies that combine antibacterial and immunomodulatory functions. Although cathelicidin LL-37 exhibits potent antimicrobial and lipopolysaccharide (LPS)-neutralizing activity,...