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Open access Jul 2026

Systematic engineering and machine learning analysis of intrinsic terminators reveal crucial nucleotides directly upstream of the terminator hairpin

This study showed that an additional adenosine nucleotide upstream of the terminator hairpin leads to improved protein production while reducing terminator read-through, revealing an important role for the nucleotides directly upstream of the terminator hairpin.

Charlotte C. Koster, B. Terlouw, Thijs Nieuwkoop et al. · 0 citations

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