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Author

H. I. Umar

2 papers indexed here

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Open access Nov 2026

In silico drug repurposing to identify activators targeting SLC7A11/xCT for cardiotoxicity: Molecular docking, dynamics simulation, and ADMET analysis

Drug-induced cardiotoxicity remains a major challenge in pharmaceutical development, necessitating the identification of protective agents against cardiac damage. The cystine/glutamate antiporter solute carrier family 7 member 11/ cystine-glutamate antiporter (SLC7A11/xCT) plays a crucial role in cellular defense a...

M. M. Alshehri, Nemat Ali, M. Alharbi et al. · 0 citations
Oct 2026

Finding Novel Inhibitors of FMS-like Tyrosine Kinase 3 from Selected FDA-approved Anticancer Drugs: Insights from Molecular Docking, MD Simulations, and ADMET Profiling.

BACKGROUND Wild-type FLT3 (WT-FLT3) has emerged as a relevant molecular target in Acute Myeloid Leukemia (AML), with increasing evidence implicating its role in leukemic proliferation and resistance, even in the absence of FLT3 mutations. Although gilteritinib is an approved FLT3 inhibitor, its efficacy in WT-FLT3 AML...

Mohammed H. al Mughram, L. J. Babatola, Md. Nazim Uddin et al. · 0 citations

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