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H. Jahr

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Review Open access Sep 2026

Lysosomal Competence in Skeletal Muscle Aging: Autophagic Flux, Measurement Gaps, and Human Translation.

Age-related deterioration of skeletal muscle contributes to loss of mobility, frailty, and disability. Altered autophagy-lysosome competence has been proposed as a mechanism linking impaired proteostasis, mitochondrial damage, inflammation, and regenerative failure to sarcopenia. Chronological muscle aging and clinical...

Oyungerel Dogsom, Jae Gyu Kim, Ye-On-Hee Lee et al. · 0 citations

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