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H. Kawashima

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Open access Aug 2026

Intra‐Accumbal Infusions of an α2‐Adrenoceptor Agonist and an α2‐Adrenoceptor Antagonist Respectively Inhibit and Enhance Acetylcholine but Not Dopamine Efflux in the Nucleus Accumbens of Freely Moving Rats

Findings indicate that RX 821002 enhances ACh efflux in the NAc by blocking accumbal α2‐adrenoceptor‐mediated inhibition of ACh release, which is implicated in cognitive impairment and systemic administration of α2‐adrenoceptor antagonists should be investigated for their potential to improve such deficits in experimen...

K. Arai, H. Kawashima, Y. Aono et al. · 0 citations

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