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Open access Sep 2026

Optimizing MRI sequence selection for glioma classification: a radiomics-based analysis of WHO CNS grade, final pathological diagnosis, and IDH status.

BACKGROUND Multi-sequence MRI protocols for glioma classification are resource-intensive, prompting the need to identify optimal, potentially reduced imaging protocols. PURPOSE To evaluate the diagnostic utility of individual MRI sequences (ASL, DWI, FLAIR, SWI, T1w, T2w) for classifying WHO CNS grade (II, III, IV),...

K. Amador, H. Kniep, J. Fiehler et al. · 0 citations
Open access Sep 2026

A comparative study of causal machine learning models for personalized treatment of acute ischemic stroke

Accurate estimation of the individualized treatment effect (ITE) is critical for supporting personalized decision-making in acute ischaemic stroke, while the average treatment effect (ATE) provides a cohort-level benchmark for method comparison and context. However, the consistency and reliability of different ca...

Vahid Farmani, H. Kniep, M. Maros et al. · 0 citations
Sep 2026

Sensitivity of Non-contrast Computed Tomography Net Water Uptake Versus FLAIR-MRI, with MR-DWI Reference Standard, for Early Detection and Physiological Characterization of Ischemic Edema in Hyperacute Stroke.

OBJECTIVE On non-contrast computed tomography (NCCT), progressive hypoattenuation can be quantified as percent net water uptake (%NWU), whereas relative fluid attenuated inversion recovery (rFLAIR)-magnetic resonance imaging hyperintensity marks later-stage vasogenic edema and blood-brain-barrier disruption. We compare...

Gabriel Broocks, A. Kemmling, René Werner et al. · 0 citations
Open access Sep 2026

Quantitative assessment of cerebral venous outflow on routine CT angiography in acute ischemic stroke.

OBJECTIVES To develop and validate a semi-automated, observer-independent method for quantitative assessment of cerebral venous outflow on routine single-phase CT angiography (CTA) in acute ischemic stroke. MATERIALS AND METHODS In this multicenter retrospective study, patients with anterior circulation large-vessel...

T. Faizy, H. van Voorst, G. Albers et al. · 0 citations

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