Review
Open access
Sep 2026
Uncovering the Potential of 3D Spheroids for Modeling the Cellular Crosstalk Within the Tumor Microenvironment in HNSCC
Head and neck squamous cell carcinoma (HNSCC) progression is profoundly influenced by dynamic cellular crosstalk within the tumor microenvironment (TME), where interactions between cancer cells, stromal components, and immune populations orchestrate therapeutic resistance, metastasis, and immune evasion. This review ex...
Anshu Yadav, Uddalak Das, Randhir Singh et al.
· Biotechnology Journal · 0 citations