Review
Open access
Sep 2026
Cellular Crosstalk at the Gut–Liver Interface in Liver Cirrhosis: Epithelial Barrier Failure, Bacterial Translocation and Immune Activation as a Bidirectional Network
The gut–liver axis is central to the systemic complications of liver cirrhosis, but it is usually described as a linear cascade in which barrier failure releases microbial products that activate a downstream immune response. This review proposes instead a four-compartment framework, in which the epithelial/barrier, inn...
T. Nitsotolis, S. Assimakopoulos, Eleftheria M. Mastoridou et al.
· Cells · 0 citations