Author

H. Munang'andu

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Open access Sep 2026

Euglena gracilis-derived β-1,3-glucan as a growth substrate for Lactococcus lactis—a snapshot of accompanying changes in transcriptomic and metabolomic profiles

β-1,3-glucan from Euglena gracilis is an emerging microalgal prebiotic. However, its potential to reprogram the metabolic profile of lactic acid bacteria has not been reported previously. In the present study, the effects of insoluble β-1,3-glucan on growth dynamics, gene expression, and the extracellular metabolit...

Hidehiko Kato, J. Nolsøe, H. Munang'andu et al. · Frontiers in Microbiology · 0 citations

Open access Sep 2026

The R plasmid pRAS2 in the fish pathogen Aeromonas salmonicida is a global mediator of antibiotic resistance in aquaculture and can be used by pRAS3 for mobilization

Horizontal gene transfer (HGT) mediated by conjugative plasmids is a major driver of antimicrobial resistance (AMR) dissemination in aquatic environments. In Aeromonas salmonicida , plasmid-mediated HGT is largely driven by the pRAS plasmid family. Here we present genomic and experimental characterization of pRAS2...

S. P. Dahal, H. Munang'andu, Asta Solberg et al. · Frontiers in Microbiology · 0 citations

Open access Jul 2026

Characterization of the conjugative modules of the pRAS4 plasmid of Aeromonas salmonicida reveals an environmental lineage

The complete sequence of pRAS4 is reported, indicating that pRAS4 is a self-transmissible R-plasmid carrying a previously uncharacterized environmental plasmid backbone, and the tetracycline Tet A efflux determinant flanked by Tn3 transposases represents a subsequent adaption under aquaculture associated antibiotic sel...

S. P. Dahal, Saurabh Dubey, H. Munang'andu et al. · Frontiers in Microbiology · 1 citation