Author

Hiromitsu Nakauchi

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Nov 2026

Adult hematopoietic stem cells activate a normally fetal-restricted program to functionally expand ex vivo.

The ability to robustly expand transplantable hematopoietic stem cells (HSCs) ex vivo enables basic science and clinical therapies otherwise hindered by the scarcity of these self-renewing multipotent cells. Despite recent improvements in long-term ex vivo HSC expansion conditions, the molecular mechanisms required for...

Kyomi J. Igarashi, M. Nicholls, Leonid Olender et al. · Blood · 0 citations

Review Aug 2026

From Gene Editing to Exogenesis: Pigs as a Source of Immune-compatible Organs for Transplantation.

These approaches offer promising strategies to expand the donor organ pool and address the growing global demand for transplantation and will be critical for widespread translation.

Asghar Ali, M. Kurome, Daniel Reichart et al. · Transplantation · 0 citations