Dengue virus (DV) is a major arboviral pathogen, with the liver being a primary target organ. The viral non-structural protein-1 (NS1) plays important roles in replication, autoimmunity, and pathogenesis, but strain-specific differences in NS1 secretion and cell responses remain incompletely understood. In this study,...
Chiroshri Dutta, H. Nath, K. Basu et al.· Virology· 0 citations
ABSTRACT Reporter-expressing recombinant influenza A viruses (IAVs) have emerged as powerful tools for studying viral infection, host–pathogen interactions, and the identification and characterization of prophylactic and/or therapeutic countermeasures for the treatment of IAV infections. By incorporating a reporter gen...
Ramya S. Barre, H. Nath, A. Nogales et al.· Journal of Virology· 0 citations
The development and implementation of this multivalent LAIV as a broadly protective pan-H5N1 LAIV for pandemic preparedness are supported and the feasibility of developing and implementing this multivalent LAIV as a broad protective pan-H5N1 LAIV against divergent H5N1 viruses for human use is demonstrated.
Ahmed M. Elsayed, Ramya S. Barre, Arash Rahmani et al.· bioRxiv· 0 citations
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