H. Parra‐Delgado

In silico approximation of the interactions of acetogenins isolated from the root of Annona purpurea with the mitochondrial complex I.

Acetogenins are polyketides found almost exclusively in plants of the Annonaceae family and exhibit diverse biological activities, including antineoplastic, antiparasitic, cytotoxic, immunosuppressive, neurotoxic, and pesticidal effects. Five highly effective acetogenins (annopurpuricins A-E) showing anticancer propert...