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H. R. Bafna

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Review Sep 2026

Lead Compound Discovery by Scaffold Hopping: Classification, Approaches and Application.

INTRODUCTION In medicinal chemistry, scaffold hopping has become a crucial strategy for identifying new lead molecules with improved physicochemical, pharmacological, and intellectual property profiles. To underline its importance in modern drug discovery and lead optimization, this study was conducted. METHODS To ga...

H. R. Bafna, N. Shirsath · 0 citations

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