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Hans Raabe

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Open access Aug 2026

A Decision Tree for Acute Oral Toxicity: Implementing the Last Resort Requirement in Practice.

Acute oral toxicity (AOT) testing is widely used for hazard identification in chemical safety assessment, but traditional animal methods are still implemented despite their scientific limitations and ethical implications. Despite the availability of non-animal methods, regulatory uptake has been inconsistent, also due...

G. Pallocca, P. Bishop, P. Browne et al. · 0 citations

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