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Author

H. Rabet

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Review Open access Sep 2026

PDCD1 SNPs and alloimmune transplant outcomes: mechanistic basis and human evidence across solid organ transplantation and allogeneic hematopoietic stem cell transplantation

Background The programmed cell death 1 gene (PDCD1) encodes programmed death-1 protein (PD-1), an inhibitory immune-checkpoint receptor that regulates peripheral tolerance and alloimmune activation. Scope This narrative review synthesizes mechanistic and human evidence linking PDCD1 single-nucleotide polymorphisms (SNP...

H. Rabet, Sayed Mostafa Hosseini · 0 citations

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