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Author

H. Ruskoaho

2 papers indexed here

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Open access Aug 2026

MiR-145-5p modulates collagen production and fibroblast behaviour after cardiac injury partially via COL5A1

In contrast to humans, zebrafish hearts after cryoinjury undergo transient fibrotic scarring that subsequently resolves and renews with functional cardiomyocytes. To understand the molecular mechanisms underlying cardiac scarring and fibrotic resolution in zebrafish, we investigated cardiac transcriptomic responses in...

Hong Wang, J. Paavola, S. Perttunen et al. · 0 citations
Open access Sep 2026

Patient-Derived hiPSC-Cardiomyocytes and Engineered Heart Tissues Reveal Distinct Functional Phenotypes in Inherited Cardiomyopathies

Background Hypertrophic and dilated cardiomyopathies (HCM and DCM) are the most common inherited cardiomyopathies. However, genotype-specific molecular and functional cardiomyocyte phenotypes and responses to neurohormonal stimulation remain incompletely understood. Here, we investigated whether patient-derived HCM and...

S. Pohjavaara, Q. Majid, L. Huttunen et al. · 0 citations

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