H. T. Soh

Charge-screening dominates signal transduction in electrochemical nucleic acid sensors for aminoglycosides

Electrochemical aptamer-based (EAB) sensors have emerged as a promising framework for reagentless, real-time molecular monitoring in complex biological matrices. Signal transduction in a prominent benchmark system—targeting aminoglycoside antibiotics—has been nearly universally attributed to target-specific, binding-in...