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Review Open access Sep 2026

The role of IL-6 in atherosclerosis: a narrative review

Atherosclerotic cardiovascular disease (ASCVD) is a chronic inflammatory disease characterized by plaque formation. Inflammatory activity, assessed by high-sensitivity C-reactive protein (hsCRP), is linked to increased ASCVD risk. Recently, there has been much interest in the association between interleukin-6 (IL-6), a...

Satoshi Yasuda, H. Tada, Junya Ako · 0 citations
Open access Sep 2026

Prevalence and Impact of a Pathogenic CYP27A1 Variant on the Phenotypes Among Patients with Monogenic Heterozygous Familial Hypercholesterolemia.

OBJECTIVE  Cerebrotendinous xanthomatosis (CTX) is a rare inherited metabolic disorder caused by pathogenic variants of cytochrome P450 family 27 subfamily A member 1 (CYP27A1). It remains unclear whether such variants modify the clinical manifestations of familial hypercholesterolemia (FH) caused by defects in the lo...

H. Tada, Atsushi Furukawa, Masayuki Takamura · 0 citations

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