Open access
Oct 2026
Inhibition of BMP–Smad1/5 signaling with DMH1 attenuates joint degeneration in a rat model of cuff tear arthropathy
Objective To characterize bone morphogenetic protein (BMP) signaling in cuff tear arthropathy (CTA) using a modified rat model (mCTA) and determine whether inhibition of DMH1-sensitive BMP type I receptor signaling attenuates CTA pathology. Design The rat mCTA model was generated by resection of the supraspinatus and i...
Tomohiro Iuchi, Kento Shimanoe, Takayuki Ide et al.
· Osteoarthritis and Cartilage... · 0 citations