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Author

H. Thakkar

3 papers indexed here

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Review Open access Aug 2026

Pharmacogenetic Predictors of Chemotherapy Treatment-Related Toxicities in Paediatric and Adolescent Acute Lymphoblastic Leukemia: A Systematic Review, Meta-Analysis and Literature-Based Candidate Prioritization

Background: Childhood and adolescent acute lymphoblastic leukemia (ALL) survival outcomes have improved significantly, but treatment-related toxicities (TRTs) remain a major concern affecting dose intensity and quality of life. Germline pharmacogenetic variations contribute to inter-individual differences in chemothera...

Santenna Chenchula, S. Srinivasamurthy, Vinnyfred Vincent et al. · 0 citations
Open access Aug 2026

Targeting Circulating Fatty Acid Binding Protein 4 Ameliorates Obesity-Associated Hepatic Steatosis.

BACKGROUND & AIMS Obesity is a major driver of metabolic dysfunction-associated steatotic liver disease (MASLD), yet the molecular mechanisms linking excess adiposity to hepatocellular lipid accumulation remain incompletely defined. We investigated whether circulating fatty acid-binding protein 4 (FABP4) mediates adipo...

Xingshan Jiang, Anthony Avellino, Jianyu Yu et al. · 0 citations

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