H. Timmers

MLL4/KMT2D mutations increase immune activity and predict therapy efficacy in colorectal cancer

KMT2D loss-of-function mutations are associated with a positive outcome of immunotherapy efficacy in CRC and responses to cisplatin treatments and the stratification of CRC patients by KMT2D gene status may enable personalized approaches by identifying CRC patient populations that benefit from ICI therapy and chemother...