Author

H. Toumi

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Open access Sep 2026

Deep transfer learning-based approaches with multimodal fusion to improve the prediction of knee osteoarthritis progression: data from the OAI and MOST cohorts

Effective diagnosis and management of knee osteoarthritis (KOA) increasingly rely on integrating diverse data sources, including imaging and clinical information. This study aimed to evaluate the use of multimodal deep learning models assisted by transfer learning (TL) to enhance the prediction of KOA progression. Deep...

Daniela Herrera, A. Almhdie-Imjabbar, Nada Ibrahim et al. · Scientific Reports · 0 citations

Review Open access Aug 2026

Piezo1 as a Key Mechanosensitive Ion Channel Linking Mechanical Overload to Mitochondrial Dysfunction, Mitophagy, and Immunometabolic Dysregulation in Osteoarthritis

Highlights What are the main findings? Piezo1 is a central mechanosensor linking pathological mechanical loading to mitochondrial dysfunction, impaired mitophagy, and immunometabolic dysregulation in osteoarthritis. Persistent Piezo1 activation may initiate a self-amplifying cascade involving calcium overload, mitochon...

H. Toumi, A. Almhdie-Imjabbar, E. Lespessailles · Cells · 0 citations