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H. Van Remmen

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Open access Jul 2026

iPLA2β: A novel store-operated calcium entry modulator contributing to muscle dysfunction during denervation

iPLA2β deletion normalizes SOCE, preserves Ca2+ homeostasis, and protects against denervation-induced muscle mass and strength loss, revealing that iPLA2β may be a critical link between oxidative stress and Ca2+ dysregulation and a promising target for mitigating muscle dysfunction during denervation.

Hongyang Xu, S. Bhaskaran, Jacob L. Brown et al. · 0 citations

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