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H. Völzke

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Open access Oct 2026

Factors associated with the transition from health to disease for type 2 diabetes, cardiovascular disease and kidney dysfunction: A NAKO-IMMEDIATE analysis

Background: Cardio-kidney-metabolic (CKM) diseases share risk factors, but their shared and distinct risk factors for disease progression remain unclear. We examined whether classical risk factors predict baseline CKM indicators and their longitudinal changes in a population-based German National Cohort (NAKO) sample....

S. G. Chiappe, K. Nimptsch, I. M. Velásquez et al. · 0 citations
Open access Sep 2026

Comparative cohort analysis of sleep-disordered breathing in German and South Korean populations.

SDB carries distinct cardiometabolic implications across German and South Korean populations, reflecting differences in adiposity related susceptibility and underlying disease burden, and AHI should be interpreted alongside population appropriate measures of adiposity and cardiometabolic risk.

M. Salanitro, A. Weihs, Seung Ku Lee et al. · 0 citations
Review Open access Aug 2026

Usual dietary intake estimation in the German National Cohort (NAKO)

Introduction Accurate measurement of dietary intake remains challenging in large-scale nutritional studies. This study aimed to develop and evaluate both a practical dietary assessment strategy and a computationally efficient statistical method for estimating usual dietary intake in the German National Cohort (NAKO Ges...

N. Wawro, Sylvia Gastell, R. Mikolajczyk et al. · 1 citation
Open access Aug 2026

Sex- and age-specific associations between body composition markers and estimated glomerular filtration rate–results of a population-based study

ABSTRACT Background Recent studies have indicated that body composition may affect kidney function. The aim of this study was to examine the sex- and age-related association between body composition markers and the estimated glomerular filtration rate (eGFR). Methods Analyses were based on data from the population-base...

Marlene Agnes Günther, T. Ittermann, H. Völzke et al. · 0 citations
Open access Sep 2026

The association of a lifestyle risk index with glycemic status in the German National Cohort (NAKO)

In this large sample of predominantly healthy adults, a combination of lifestyles, foremost driven by not smoking, was weakly associated with lower HbA1c levels but not self-reported diabetes, and lifestyle factors may be relevant for glycemic control.

G. Maskarinec, Rebecca Klapp, U. Nöthlings et al. · 0 citations
Open access Aug 2026

Volumetric reference data of the orbit: a deep learning MRI analysis in the German national cohort

This deep learning tool effectively resolved the bottleneck of manual segmentation, providing comprehensive orbital reference data for the German population and enabling future high-throughput epidemiological research into the associations between orbital anatomy, systemic health, and disease.

Navid Farassat, M. Reisert, S. Rospleszcz et al. · 0 citations

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