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Open access Sep 2026

Quantitative μ-Opioid Receptor PET with [18F]FCFN in Nonhuman Primates: Naloxone Blockade and Within-Scan Displacement

Background/Objectives: Quantitative PET imaging of μ-opioid receptor (MOR) availability and pharmacologic engagement can advance in vivo studies of opioid receptor biology. We previously evaluated a series of 18F-labeled carfentanil analogs and prioritized the regioisomer [18F]fluorocarfentanil ([18F]FCFN) based on fav...

Evan Gallagher, Joseph W. Downey, Chi-Hyeon Yoo et al. · 0 citations
Open access Aug 2026

Human cerebral cortex organization characterized by functional PET-FDG "Metabolic Connectivity".

This study characterizes the spatiotemporal organizational principles of RSMC, deepening insight into the brain's energetic framework and providing a basis for future cognitive and clinical investigations of metabolic connectivity organization.

Penghui Du, Sean E. Coursey, Ting Xu et al. · 0 citations

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