Candida
infections remain difficult to treat because of antifungal resistance, toxicity, and suboptimal pharmacokinetics. This study comparatively evaluated fourteen structurally diverse flavonoids against
Candida albicans
,
Candida glabrata
, and
Candida krusei
to identify structure–activity, mechanistic, a...
H. Y. Teruna, Fauzan Zein Muttaqin, Neni Frimayanti et al.· ChemistrySelect· 0 citations
A series of novel chalcone–quinoline–triazole hybrid compounds were rationally designed, synthesised, and evaluated for antifungal activity against clinically relevant Candida species, including C. albicans, C. glabrata, and C. krusei. Among the synthesized derivatives, compound 7b exhibited the most potent antifungal...
R. Hendra, Rahmad Setiawan Rabby, Tengku Anggia Fitri et al.· Medicinal Chemistry Research· 0 citations
Malaria caused by Plasmodium falciparum remains a major global health burden, and the increasing resistance to conventional antimalarial drugs urgently demands the discovery of novel bioactive compounds from natural sources. This study aimed to evaluate the antiplasmodial potential of methanol extract from Persea ameri...
S. Fauza, Elva Susanty, H. Y. Teruna· Journal of Community Health...· 0 citations
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