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Author

H. Y. Teruna

3 papers indexed here

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Sep 2026

Anti‐ Candida Flavonoid Leads: Mechanistic Evaluation and Early Safety Assessment

Candida infections remain difficult to treat because of antifungal resistance, toxicity, and suboptimal pharmacokinetics. This study comparatively evaluated fourteen structurally diverse flavonoids against Candida albicans , Candida glabrata , and Candida krusei to identify structure–activity, mechanistic, a...

H. Y. Teruna, Fauzan Zein Muttaqin, Neni Frimayanti et al. · 0 citations
Open access Aug 2026

Design and mechanistic evaluation of chalcone–quinoline–triazole hybrids as antifungal CYP51 inhibitors

A series of novel chalcone–quinoline–triazole hybrid compounds were rationally designed, synthesised, and evaluated for antifungal activity against clinically relevant Candida species, including C. albicans, C. glabrata, and C. krusei. Among the synthesized derivatives, compound 7b exhibited the most potent antifungal...

R. Hendra, Rahmad Setiawan Rabby, Tengku Anggia Fitri et al. · 0 citations
Open access Aug 2026

Antiplasmodial Activity and Interactions of Persea americana Seed Flavonoids Against Plasmepsin II

Malaria caused by Plasmodium falciparum remains a major global health burden, and the increasing resistance to conventional antimalarial drugs urgently demands the discovery of novel bioactive compounds from natural sources. This study aimed to evaluate the antiplasmodial potential of methanol extract from Persea ameri...

S. Fauza, Elva Susanty, H. Y. Teruna · 0 citations

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