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Open access Sep 2026

Nanocarrier-enabled restoration of miR-34a by Ailanthus excelsa Roxb. phytochemicals directly target NOTCH1 signaling to suppress cancer stemness in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype associated with poor prognosis, metastasis, and limited targeted therapies. This study developed a folate-functionalized chitosan nanoparticle system targeting the miR-34a/NOTCH1 signaling axis and evaluated its anticancer potential using...

C. Ukwubile, A. A. Ahuchaogu, Anietie Eyo Robert et al. · 0 citations

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