Author

H. Zgurskaya

2 papers indexed here

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Open access Nov 2026

A substrate-dependent mechanism of inhibition of the polyspecific multidrug efflux pump MexF from Pseudomonas aeruginosa

ABSTRACT Pseudomonas aeruginosa presents a significant challenge in both clinical and antibiotic discovery settings due to the low permeability of its cell envelope. Efflux pumps acting synergistically with the permeability barrier of the outer membrane provide efficient protection against various antibacterial agents....

Muhammad R. Uddin, J. Mehla, R. Kinthada et al. · Antimicrobial Agents and Che... · 0 citations

Open access Oct 2026

Small proteins CrgA and Rv0207c modulate the essential mycolic acid transporter MmpL3.

MmpL protein complexes are major contributors to lipid/metabolite and drug transport in Mycobacterium tuberculosis and related mycobacteria and are important targets in current drug discovery efforts. At the core of these complexes are proton-motive force driven transporters belonging to the Resistance-Nodulation-cell...

K. Choukate, Svitlana O. Babii, Wei Li et al. · Journal of Biological Chemis... · 0 citations