Open access
Aug 2026
Aberrant excitatory neuronal ERBB4 promotes Alzheimer’s disease pathology
It is demonstrated that, during AD progression in mice, astrocytes and microglia increase phagocytic elimination of excitatory synapses while reducing elimination of inhibitory synapses, suggesting that neuroinflammation alone may be dispensable for early AD synapse loss.
Seyoung Lee, Eunseok Park, Ha-Eun Lee et al.
· Nature · 2 citations
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