Hackwon Do

Structural Insights into the N-Terminus and a Flexible P-x-P Loop near the Active Site of a Class III Aminotransferase

Class III aminotransferases represent a structurally and functionally unique subgroup. However, the contribution of specific loop elements to their active-site architecture and cofactor-dependent structural transitions remain underexplored. We elucidated the structural framework underlying the catalytic function of cla...