Author

HaeIn Kim

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Aug 2026

Discovery of acridone analogs as novel entry inhibitors targeting e protein of dengue virus.

The envelope (E) protein of the Dengue virus (DENV) is critical for virion attachment and membrane fusion with the host cell, as well as the release of the viral RNA genome into the cytoplasm. In this study, we describe the design, synthesis, and biological evaluation of novel viral entry inhibitors containing an acrid...

Dabeen Lim, Chanwoo Lee, Jihun Kim et al. · Bioorganic chemistry (Print) · 0 citations

Jul 2026

IFITM3 promotes triple-negative breast cancer progression by regulating β-catenin localization.

Interferon-induced transmembrane protein 3 (IFITM3) is best known as an antiviral protein, but accumulating evidence supports pro-tumorigenic functions across several cancers. Here, we examined IFITM3 in triple-negative breast cancer (TNBC). IFITM3 depletion suppressed MDA-MB-231 cell proliferation, migration, sphere f...

Heeyeon Kim, Young-Ming Yu, Y-U Park et al. · Biochemical and Biophysical... · 0 citations