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Hai-Dong Cheng

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Review Open access Sep 2026

Molecularly informed preoperative and response-adapted management of colorectal cancer: evidence, decision boundaries, and emerging directions

Treatment delivered before surgery in colorectal cancer now encompasses several clinically distinct strategies rather than one uniform pathway. These include selective neoadjuvant chemotherapy for radiologically high-risk colon cancer, total neoadjuvant therapy (TNT) and response-adapted organ preservation in rectal ca...

Wen Hao, Yan Liu, Hai-Dong Cheng et al. · 0 citations

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