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Hai-Kuo Zheng

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Open access Sep 2026

Beyond anticoagulation: Rivaroxaban attenuates acute myocardial inflammatory injury through the PAR2-mROS-TXNIP-NLRP3 pyroptosis axis.

BACKGROUND Excessive inflammation and oxidative stress are major drivers of myocardial injury following acute myocardial infarction (MI). NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome-driven pyroptosis is the central underlying mechanism of the inflammatory response. In parallel, factor Xa (FX...

Qian Zhang, Wei-Wei Chen, Maralmaa Tsagaankhuu et al. · 0 citations

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