Author

Hai-Lin Chen

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Review Open access Aug 2026

Syndrome differentiation and treatment of pediatric central precocious puberty: role of the spleen-kidney axis

The role of kidney and spleen dysfunction is discussed and the underlying mechanisms are explored – particularly in the context of the neuro-endocrine-immune network that links central neuroendocrine activation with peripheral immune-metabolic signals.

Yu-Jun Luo, Chao-Jie Huang, Yanbing Lu et al. · Frontiers in Immunology · 0 citations

Open access Aug 2026

Insomnia Increases Susceptibility to Sciatica: Evidence from Mendelian Randomization and Integrative Genetic Analyses

Background Neuropathic pain (NP) frequently co-occurs with sleep disorders, yet the causal relationship between the two remain unclear, necessitating further investigation to elucidate their intrinsic connection. Methods We conducted linkage disequilibrium score regression (LDSC), Mendelian randomization (MR), multivar...

Shuyan Li, Xianmei Chen, Hai-Wen Cen et al. · Journal of Pain Research · 0 citations