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Hai-Ling Zhao

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Open access Oct 2026

Tetrandrine attenuates diabetic kidney disease by suppressing the TLR4-NF-κB-NLRP3 inflammatory signaling pathway in proximal tubular cells.

BACKGROUND Diabetic kidney disease (DKD) involves persistent tubular inflammation. Tetrandrine (Tet), a bioactive alkaloid from Stephania tetrandra S. Moore, has renoprotective potential, but its effects on TLR4-associated inflammatory signaling remain incompletely understood. METHODS Male KK-Ay mice received Tet (10...

Yan Yan, Wen-Ru Wang, Heng Chen et al. · 0 citations

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