Open access
Sep 2026
Immune heterogeneity-driven therapeutic responses to platelet-rich plasma and TRPV1 antagonism in osteoarthritis
Introduction Osteoarthritis (OA) exhibits substantial heterogeneity in synovial immune profiles, which may underlie variable analgesic responses to standard biological and neuromodulatory treatments. Remodeling the immune microenvironment while targeting nociceptive pathways may improve therapeutic consistency. Methods...
Peng Liu, Jing-Wei Zhu, Yang Yang et al.
· Frontiers in Pharmacology · 0 citations