Review
Aug 2026
Exploring ULK family in human cancer: insights into mechanisms and therapeutic potential.
The ULK (Unc-51-like kinase) family, a group of serine/threonine protein kinases, plays a central regulatory role in the initiation of autophagy. Autophagy has a dual role in cancer, as it can both inhibit tumor formation and promote the survival and progression of established tumors, making targeting autophagy an attr...
Mengjia Li, Mengqi Zhang, Chenlin Wen et al.
· Bioorganic chemistry (Print) · 0 citations