Hai-Wen Wang

Fyn kinase: a key mechanistic regulator and therapeutic target in tauopathy and neurodegenerative diseases

Synaptic dysfunction and intracellular accumulation of pathological tau are convergent hallmarks of Alzheimer’s disease (AD) and related tauopathies, yet the molecular mechanisms coupling these events to widespread neurodegeneration remain incompletely understood. The Src family kinase Fyn has emerged as a critical sig...