Open access
Aug 2026
ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration
This study reveals the WTAP/ACSL4/IGF2BP2 axis as a mediator of IL‐1β‐induced LMP via m6A‐dependent lipid peroxidation, highlighting a potential therapeutic target for IVDD.
Shu Jia, Xu Gao, Lai-Min Zhu et al.
· Advancement of science · 0 citations