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Author

Haider Sami

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Open access Sep 2026

The Cytoplasmic MicroRNA‐Production Complex Regulates MicroRNA Sorting to Extracellular Vesicles During Synaptogenesis

ABSTRACT Extracellular vesicles (EVs) have emerged as novel players of cell communication, in part via the transfer of microRNA (miRNA) cargo to recipient cells. Although several RNA‐binding proteins (RBPs) were shown to shuttle miRNAs to EVs, how they are loaded with miRNA is unknown. This study demonstrates that the...

Yu-Zhou Zeng, Selina Luhmann, Aditi Saha et al. · 0 citations
Jul 2026

Dichotomies in Ex Vivo and In Vivo Performance of Receptor-Binding Mutants of Adeno-Associated Virus Vectors

In vivo performance diverged sharply from ex vivo findings as AAV2ΔHSPG and AAV2ΔHSPG and AAV2ΔHSPGΔIntegrin observed a substantially enhanced transduction in multiple non-hepatic tissues, as well as a strong liver detargeting, while AAV2ΔIntegrin was non-infectious in vivo.

Olaniyi Olarewaju, Martin Bentler, Jacqueline Breuer et al. · 0 citations

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