Nystose treats intervertebral disc degeneration via the Nrf2 axis: a focus on oxidative stress and ferroptosis
Background Intervertebral disc degeneration (IDD) is the primary aetiology of chronic lower back pain and is driven by factors such as oxidative stress and nucleus pulposus (NP) cell dysfunction. Nystose (Nys), a key active oligosaccharide derived from Morinda officinalis How., has shown potential in treating degenerat...